Wednesday, May 15, 2019

Malaria Essay Example | Topics and Well Written Essays - 2000 words

Malaria - Essay Examplegenus Anopheles plays a pivotal role in the development of malaria parasite. The maturation of the microbe from the gametocytic stage to the sporozoite stage takes place inside the body of the female Anopheles. The body of the mosquito provides ambient temperature and humidness to the developing microbe and the female survives long enough to allow the parasite complete its lifecycle in the mosquito body. Anopheles breed on water and each species has its own preference when it comes to selection of breeding place for simulation some like puddles, shallow water, fresh water or even hoof prints. b. Apicomplexa protozoa Plasmodium Apicomplexans are also known as sporozoans. All apicomplexans are obligatory and intracellular microbes i.e. they need to set down at least some part of their life cycle within an animal host. Important characteristics of apicomplexans embarrass the presence of tiny organ like structures which are present at the very tips of the cells . These tiny organ-like structures ask enzymes which helps the microbe penetrate into the host tissue. One of the most well known and pathogenic genera of apicomplexans includes Plasmodium- which causes malaria. Plasmodiums lifecycle is spent in two stages- in the body of mosquitoes and that of globe. It ultimately affects humans and causes rupture in the prodigal vessels. There are more than 100 Plasmodium species which can infects living organisms however further 4 of these species cause infection in humans- Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale and Plasmodium malariae. The lifecycles of the four species affecting humans are similar. Lifecycle The lifecycle begins when a female Anopheles carrying malaria parasite sucks... The paper talks about the cause of Malaria, lifecycle, diagnosis and treatment, development of a vaccine, advanced prophylaxis.According to the paper it is needless to say that malaria has been a curse on human health. However, the recent advances in development of vaccination are quite promising. Efforts need to be make to spread awareness about diagnosis and treatment to people who may not have gravel to them especially in the poor tropical countries. Future research should aim at not only developing vaccines but also developing better chemoprophylaxis agents.Worldwide the Anopheles mosquito is known as malaria mosquito because it is considered to be the primary vector for malaria. The genus Anopheles mosquito is found worldwide except for in Antarctica. The affection is transmitted by the female anopheles. As the report says since malaria is worldwide public health problem, researchers have been trying to develop vaccines against the disease to lend protection against the parasites. The development of a vaccine would mean lower mortality, morbidity and economic be involved with the treatment of the disease, awareness programs etc. the aim of the researchers are to wipe the disease from the earth.It was first i n 1960, that it was thought that the development of a vaccine for malaria was feasible. It was seen that IrSp (irradiated sporozoites) rendered rodents immunized. Next the IrSp vaccine was tested on human volunteers with anopheles bite and it was seen that the vaccine was highly species specific. The multifactorial protection given by the vaccine involves direction of neutralized antibodies against circumsporozite and it is this idea that is today being researched upon to develop a better and much effective vaccine.

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